Where more specifically?
It will be colder than you are used to. Parts of Pennsylvania are former manufacturing areas that are now on hard times. People may be initially uncertain of how to deal with you in a small town but they should be friendly soon enough if you are nice. The Amish are pretty cool if you're close to them, make good stuff. Don't freak out if you find a bicycle and clothes on your property one day, it's just an Amish teenager's stash for when they try to sneak out of their parent's home.