Kusokora is basically remixing images. like "exploitable" or something like that. Literally means "shit collage"
The hashtag means "Aren't-they-all-the-same shit collage grand prix"
All of the remixes leave that line unchanged, and usually a couple of other lines in the panel afterwards, but in this particular instance they got edited.
Note that the spelling-to-personality correspondence might not be canon, but it doesn't really matter. The point is she has multiple personalities.
This is the protagonist "Lain" (in kanji)
This is the other protagonist "Lain" (in katakana)
Who seduces a grade school boy and brings him to her room
"lain" (in roman alphabet)
Has a lovely smile when she spies on her girlfriend's fa**ing.
"Lain" (in hiragana)
A rare character that doesn't get much screen time. Defeat her and you go to the bonus stage.
Right is "Lain" (kanji) and left is "Lain" (hiragana)
Aren't they all the same!?
Lain has many forms
Let's all love Lain!
Game version "Lain" (kanji)!
Fucked up in all the places where the anime version is nice.
Original character designer Yoshitoshi Abe's version
Initial depictions are childish, later ones are more mature