Mechwarrior famously uses heat generation as a limiting factor for your offensive capabilities. Weapons generate heat, you can only dissipate so much heat so fast, so you can't generally fire every single weapon at an enemy repeatedly, you need to stagger your shots so you don't overheat your battlemech and force a core shutdown.
Similarly, there could be a watt meter in the bicycle simulator video game and an endurance meter modelling lactic acid production/removal and you could be tasked with keeping these meters in check while simultaneously going as fast as possible.
Couple that with taking the correct line on corners, avoiding obstacles, bike messenger fetch quests, I dunno. It could be fun.