I don't know if either of these mangaka solely create their manga with their computers, but the authors of Tsugumomo and Takagi-san often stream themselves drawing their manga.
Tsugumomo's author, especially, makes use of programs to both model the 3D spaces he draws his characters in and the characters themselves. I can't remember the name of the character modeling program, but I think it had "doll" in the name. Because of that, everything in the manga honestly looks amazing. The only problem I have with it is the characters sometimes look a little stiff, but that's mostly when they're colored. Also, know that it's pretty lewd, if you decide to read it.