Drones are going to hit you a lot. Shit sucks, sometimes REALLY sucks, but it's not the end of the world, so it's important to recognize how they work. A drone gets off 3, sometimes 4 shots before your first volley; whenever it moves to attack, pause and try and eyeball where it's targeting. If it's an empty room or the med bay, fine. If it's pointing at your weapons or cloaking, cloak and get it to fuck off. You'll still get the first volley by delaying their weapons, and it's worth giving up the second to get a shot at breaking their drones.
Now that I think about it, you could probably do this with weapon shots two. That might be useful in some situations. Enemy has a basic laser and BL2, pause and check if the basic laser is worth cloaking for or if you should wait to dodge the BL2. Might be worth thinking about.
Always always always avoid asteroids. It's never worth it. Asteroid field shots are based on your shield system level, so it'll be the lightest asteroid barrage you've ever seen, but it's still not worth it. If you meet a bad ship in an asteroid field then you're probably dead.
...I think. I haven't actually tried this much. There might be some situations where it's worth the risk.
Pulsars are as much a coin flip for you as it is for any ship. Some people avoid this like the plague, I don't really mind them.
Suns, on the other hand, ain't shit. Take a sunless fight over a sunny one, but take a sunny fight over an empty beacon. If you kill them in two volleys, which isn't anything uncommon, then you can get out of there before the first flare. If not, then you often escape before the second. The flares do hurt a bit without shields, but even then it's nothing that bad. Many times I don't kill with the first two volleys, eat a flare, kill them with the third volley, and still have time to get the ship ready for the next fight before the next flare.